Bansal, Kuldeep K. and Mishra, Deepak K. and Rosling, Ari and Rosenholm, Jessica M. (2019) Therapeutic Potential of Polymer-Coated Mesoporous Silica Nanoparticles. Applied Sciences, 10 (1). p. 289. ISSN 2076-3417

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Abstract

Mesoporous silica nanoparticles (MSNs) find tremendous applications in drug delivery due to several advantages such as their easy fabrication process, high drug loading, biodegradability, biocompatibility, and so forth. Nevertheless, despite several advantages, the use of this striking drug delivery carrier is restricted due to premature drug release owing to the porous structure. Coating of the pores using polymers has emerged as a great solution to this problem. Polymer coatings, which act as gatekeepers, avoid the premature release of loaded content from MSNs and offers the opportunity for controlled and targeted drug delivery. Therefore, in this review, we have compiled the polymer-based coating approaches used in recent years for improving the drug delivery capability of MSNs. This manuscript provides an insight into the research about the potential of polymer-coated MSNs, allowing the selection of right polymer for coating purposes according to the desired application.

Item Type:	Article
Subjects:	Biomedical Science Biochemical and Biophysical Sciences
Depositing User:	RCB Library
Date Deposited:	02 Aug 2021 08:09
Last Modified:	02 Aug 2021 08:09
URI:	http://rcb.sciencecentral.in/id/eprint/236

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