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Pandey, Manish and Bansal, Sakshi and Chawla, Geetanjali (2019) Molecular Approaches for Analysis of Drosophila MicroRNAs. In: Fundamental Approaches to Screen Abnormalities in Drosophila. Springer Protocols Handbook, pp. 169-188.

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Abstract

MicroRNAs (miRNAs) belong to a class of small non-coding endogenous RNAs that regulate gene expression at the post-transcriptional level. These small RNAs recognize sequences within 3′ untranslated regions of target mRNAs in complexes referred to as a miRNA-induced silencing complex (miRISC). Drosophila melanogaster has served as an indispensable model system for defining the diverse biological roles of miRNAs, their mechanism of action as well as the role of miRNA biogenesis factors. In this chapter we describe some of the assays used for molecular analysis of Drosophila miRNAs.

Item Type: Book Section
Subjects: Biomedical Science
Depositing User: RCB Library
Date Deposited: 21 Jun 2022 06:13
Last Modified: 21 Jun 2022 06:13
URI: http://rcb.sciencecentral.in/id/eprint/248

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