Bhattacharya, Sulagna and Agarwal, Sakshi and Shrimali, Nishith M. and Guchhait, Prasenjit (2021) Interplay between hypoxia and inflammation contributes to the progression and severity of respiratory viral diseases. Molecular Aspects of Medicine. p. 101000. ISSN 00982997

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Abstract

History of pandemics is dominated by viral infections and specifically respiratory viral diseases like influenza and COVID-19. Lower respiratory tract infection is the fourth leading cause of death worldwide. Crosstalk between resultant inflammation and hypoxic microenvironment may impair ventilatory response of lungs. This reduces arterial partial pressure of oxygen, termed as hypoxemia, which is observed in a section of patients with res-piratory virus infections including SARS-CoV-2 (COVID-19). In this review, we describe the interplay between inflammation and hypoxic microenvironment in respiratory viral infection and its contribution to disease pathogenesis.

Item Type:	Article
Subjects:	Biomedical Science
Depositing User:	RCB Library
Date Deposited:	29 Jul 2021 07:44
Last Modified:	29 Jul 2021 07:44
URI:	http://rcb.sciencecentral.in/id/eprint/622

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